Research Highlights

Precision Medicine Research is Part of Singapore’s RIE2025 Strategic Goal to Transform and Protect the Health of Every Singaporean

Our research will focus on accelerating health research by combining genetic, lifestyle, clinical data and other molecular technologies to understand how these factors impact health and/or contribute to disease.

We hope to generate new findings that will inform healthcare practices with the goal of improving the efficiency and effectiveness of disease prevention, diagnosis and treatment.

Research Highlights

Evaluating data requirements for high-quality haplotype-resolved genomes for creating robust pangenome references	A catalogue of structural variation across ancestrally diverse Asian genomes	The Singapore National Precision Medicine Strategy
Analysis of clinically relevant variants from ancestrally diverse Asian genomes	Sharing precision medicine data with private industry: Outcomes of a citizens’ jury in Singapore	Genetic Variation Influencing DNA Methylation Provides Insights into Molecular Mechanisms Regulating Genomic Function
GA4GH: International Policies and Standards for Data Sharing across Genomic Research and Healthcare	Mapping Genomic and Epigenomic Evolution in Cancer Ecosystems	Trust and Trade-Offs in Sharing Data for Precision Medicine: A National Survey of Singapore
Religious Perspectives on Precision Medicine in Singapore	Family history assessment significantly enhances delivery of precision medicine in the genomics era	“Who is watching the watchdog?”: Ethical perspectives of sharing health-related data for precision medicine in Singapore
Adiposity and metabolic health in Asian populations: an epidemiological study using dual-energy x-ray absorptiometry in Singapore	A global initiative to deliver precision health in diabetes	Clinical Implementation of Nephrologist-led Genomic Testing for Glomerular Diseases in Singapore